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Don’t write off A380, but global vaccine crucial

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Emirates Airline president Tim Clark expects the Airbus A380 will continue to be a “hugely potent” tool once the industry begins recovering from the post-coronavirus crisis. But he warns that it will hinge on the roll-out of a global inoculation programme against the disease. (www.flightglobal.com) Más...

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canuck44
canuck44 6
One should not bet the farm or the airline on the development, successful testing, manufacturing and universal distribution of a vaccine that remains effective over time even as the virus undergoes change. We have a mixed record on vaccines for those which are respiratory viral pathogens primarily as some remain stable to the target antigen while others like influenza mutate continuously. We still do not have a vaccine for SARS which is a COVID-2 virus or a cousin of our current COVID-19.

Two mechanisms will make us all less susceptible. Herd immunity we hear about regularly is when a high proportion of the population has resistance. Some diseases like pertussis and measles require a high level of over 90% of the population to have this immunity while others a lower percentage is all that is needed. We have no idea on what level is necessary for COVID-19 to drop from this mechanism.

The second is attenuation. As viruses pass through mammals the infectivity of the virus decreases. Live polio vaccine is an example of using this mechanism where the virus taken by mouth has been weakened to not cause disease in patients with intdact immune systems.

Finally treatment. The only sure treatment is using convalescent antibodies from a recovered patient's plasma. Obviously not first line.
aurodoc
aurodoc 5
Risk is just a part of life. Influenza causes huge numbers of illness and death every year. We get flu vaccine based on what types are expected for the year but it has been wrong in the past. Also only half of people in US get the flu vaccine. When you get on a plane bus train or elevator for that matter you are at risk for getting transmission. We did it routinely before Covid 19 and will do so after we get better control and understanding of this virus
TorstenHoff
Torsten Hoff 4
Great summary. One thing worth noting is that unless we get COVID-19 under control, ALL forms of mass transportation are in jeopardy, whether it is a plane, a subway, or a bus.

On a subway and bus, people are even more closely crammed in, and the turnover of passengers getting on and off is obviously greater than on an airplane, meaning that the number of people in your immediate vicinity that you are exposed to is greater, too.
yr2012
matt jensen 0
And there's no vaccine for the common cold or flu either
jb747
John Bartels 1
I don't think there's ever been quite the same level of incentive...
imtxsmoke
Jeffrey Bue 5
I always thought that the cold virus vaccine has never materialized because there are too many different virus’ and therefore a vaccine would be ineffective
skylane777
John Nichols 3
With respect, tilting at windmills is not good public policy. As stated, SARS has no immunological preventative. Ebola, Hanta, and others remain potent and to some extent quite lethal pathogens. Never before this policy of quarantining the healthy has such a strategy been enacted. It may serve to isolate people from the pathogen, and vice versa, but it is merely prolonging the wait for the inevitable. Flus have been ravaging our societies for as long as man has been present, and other organisms before that. Shutting down commerce and markets is a form of governmentally commanded suicide for our life style. The mystery surrounding the genesis of the novel flu provides fodder for the “terrror merchants” which make millions of people compliant with terrible would be “solutions”. Transportation is an integral part of our economy., and no special solution is available to make it immune to risk.
azuresc
Lanny Word 4
Comparing COVID-19 to Ebola and Hanta is comparing apples to Oranges. Now SARS is a much closer comparison but still vastly different in when it starts to transmit. That is one of the reasons SARS was able to be contained so quickly. When you have a two week window to test and isolate, containment becomes exponentially easier. As for the political and economical issues intertwined in it all, we are probably of a much similar mindset. So don't take any of this as picking a fight.

crk112
crk112 0
Big pharma sure is powerful... they're getting as many CEOs and businessmen as possible to push for mass vaccination... so they can shoot you up with sugar water and charge you hundreds of dollars for it.

Almost as laughable as if they started trying to vaccinate for the common cold.

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